How to Test Oxycodone & Percocets

February 24, 2025

Oxycodone/Percocet is one of the most commonly asked-about substances from our community. While our Heroin & Pain Pills Spot Kit Package is our clear recommendation for oxycodone and Percocet testing, the color change results are not always as straightforward as other substances.

Generally, pressed pills can be difficult to screen with reagents, due to pill binders, ingredient mixtures, and manufacturing remnants. To help break down this process, we have created this guide to explain how the color changes may appear, and how Percocet results may differ from plain oxycodone pill results.

What is in a Percocet? Is Percocet the same as oxycodone?

Oxycodone, also known as Oxycontin, “Oxy,” and “OC,” is a semi-synthetic opioid used for pain management. Percocet is the brand name for pills that contain oxycodone and acetaminophen (also known as paracetamol).

Percocet Test Kit and Oxycodone Test Kit

Percocet pills are also called “Oxycodone/Acetaminophen 5-325,” because the mixture often contains 5 milligrams of oxycodone and 325 milligrams of acetaminophen. Other mixtures are also common, such as 2.5 mg/325 mg, and 7.5 mg/325 mg. While oxycodone and Percocet share the same active ingredient, and both have a high potential for abuse, their effects and risks are not identical. The same milligram amount of oxycodone in a Percocet pill may feel stronger than oxycodone alone, due to the compounding effects of the acetaminophen. However, others have reported that oxycodone alone produces stronger feelings of euphoria.

What does Percocet look like?

There are many appearances prescription Percocet can take—yellow and oval-shaped, white and round, blue and round, white and oval shaped, and more. However, despite these common appearances, it is impossible to tell if a Percocet is legitimate just by looking at it. Some believe you can identify legitimate pressed pills based on the quality of the press, or the numbering or lettering on the front. Unfortunately, identifying a pill as legitimate or counterfeit purely based on visual appearance is an unreliable, and even dangerous, method of screening.

Unless you have personally obtained a pharmaceutical tablet from a prescription, it is impossible to know if it is legitimate. Using an at-home test kit, or a mail-in lab testing service is the only way to identify if oxycodone is present in your pill, and if other cutting agents are absent. See Oxycodone Drug Test at the bottom of the page for more information on the best test kits to use for Oxycodone and Percocet.

Counterfeit Pills Sold As Percocet graphic, showing pills sold as oxycodone/acetaminophen 525 that contained fentanyl and nitazenes.

Testing Oxycodone/Acetaminophen 5-325 mg

Oxycodone and Percocet (Oxycodone/Acetaminophen) can be complicated to test. Generally, pressed pills are notoriously difficult to test, due to the pill binders, fillers, inactive ingredients, and remnants from the manufacturing process affecting reagent results.

With oxycodone specifically, varying ingredient mixes—like the Percocet mix of oxycodone and acetaminophen—can also change the way a color result appears, often reacting completely differently than pills only containing oxycodone.

While we recommend the Heroin & Pain Pills Spot Kit Package to test oxycodone or Percocet, we have listed the common variations in reactions that are seen and accepted for oxycodone and Percocet:

Marquis should either not react (stay clear) or turn a slow, faint purple.
Mecke should either not react or turn a yellowish/light green color.
Froehde should react either sky blue (with acetaminophen) or yellow.
Mandelin can react in a variety of ways, either not reacting at all (staying yellow with no changes), or reacting light orange/brown, bluish green, or blue/gray/green (with acetaminophen mixes).
Liebermann may react with brown spots, or may turn rusty reddish brown.

Check out all of our oxycodone and Percocet (oxycodone/acetaminophen 5-325 mg) reactions on our app, and our Vimeo page.

Oxycodone Drug Test | Percocet Drug Test

For testing oxycodone or Percocet (oxycodone / acetaminophen) with an at-home test kit, we recommend the Heroin and Pain Pills Spot Kit Package. This kit includes the Marquis, Mecke, and Froehde reagents, along with 10 fentanyl test strips, which will positively identify oxycodone, and rule out potential cutting agents, like fentanyl.

Additionally, with the rise in the presence of xylazine and nitazenes being found in opioids—two dangerous cutting agents affecting black market opioids—we also recommend testing with Nitazene Test Strips and Xylazine Test Strips.

Nitazene Test Strips for Oxycodone and Percocet

Oxycodone Test Kit and Percocet Test Kit, with Fentanyl Test Strips

Xylazine Test Strips for Oxycodone and Percocet

While these test kits are excellent at-home testing options, the most accurate way to fully screen an oxycodone or Percocet pill is to send a sample into a lab for testing. At our lab, Transparency Testing, the Complete Analysis (Purity + Identification) will detect all substances present, and provide the amounts of each substance. If you only want to see what components are present, the Full Identification Analysis is another option for screening oxycodone and Percocet.

Get our Oxycodone & Percocet Test Kit here, along with Nitazene Test Strips, and Xylazine Test Strips. To see our oxycodone and Percocet (oxycodone/acetaminophen 5-325 mg) reaction videos, download our app, or check out our Vimeo page.