Stimulant, Entactogen

Methylone is a novel stimulant-entactogen substance of the cathinone class, and is part of the group of substances referred to as “bath salts.” Methylone is sometimes used as a substitute for MDMA due to similarities in their effects. Alexander Shulgin commented that the substances has “almost the same potency of MDMA, but it does not produce the same effects.” He also stated that it “has an almost antidepressant action, pleasant and positive, but not the unique magic of MDMA.”


Subjective effects include stimulation, spontaneous physical sensations, tactile enhancement, increased heart rate, increased perspiration, increased blood pressure, temperature regulation suppression, dehydration, vibrating vision, anxiety suppression, disinhibition, cognitive euphoria, increased capacity for empathy, psychosis, time compression, thought acceleration, motivation enhancment, and wakefulness.

Methylone was first synthesized by chemists Peyton Jacob III and Alexander Shulgin in 1996 as a potential antidepressant. The toxicity of methylone has not been well-studied, although it likely does not exceed that of MDMA, and it has a limited history of human usage.