Amphetamine is a classical stimulant substance of the phenethylamine class. It is the parent compound of the substituted amphetamines, a diverse group that includes methamphetamine, MDMA, cathinone, and bupropion. The mechanism of action involves promoting release of the neurotransmitters dopamine and norepinephrine

Alpha-methylphenethylamine, Amfetamine, Speed, Adderall, Dexedrine and Tentin

Subjective effects include stimulation, focus enhancement, motivation enhancement, increased libido, appetite suppression, and euphoria. It is usually taken orally, but can also be insufflated, injected, or administered rectally. Lower doses tend to increase focus and productivity, while higher doses tend to increase sociability, sexual desire, and euphoria.

It was first synthesized in 1887, but its psychostimulant effects were not discovered until 1929. In the 1930s, it was sold over-the-counter under the name “Benzedrine” as a decongestant. It became widely used to treat a range of ailments, such as alcohol hangover, narcolepsy, depression, and obesity. Due to issues with addiction and abuse, it was eventually listed as a controlled substance under the United Nations 1971 “Convention on Psychotropic Substances”.

Oral, Snorted, Injected, Rectal