The drug supply is evolving again. Just when public health agencies and harm reductionists were starting to wrap their heads around xylazine and nitazene, a new veterinary sedative has entered the scene: medetomidine. It's stronger, less predictable, and even more dangerous. What Is Medetomidine, and Why Is It in the Fentanyl Supply? Medetomidine is a...
In our previous blog post, we explored the fascinating chemistry and effects of 1P‑LSD and its analogues. But one crucial element deserved its own deep dive: the rise of prodrugs in the research chemical (RC) world and how they reshaped the psychedelic landscape. If you’ve ever wondered how “legal LSD” became a thing...
A groundbreaking phase two clinical trial has found that a single 100-microgram (ug) dose of LSD, in its pharmaceutical formulation MM120, can significantly reduce symptoms of generalized anxiety disorder (GAD). What makes this finding especially noteworthy is that the relief lasted for up to twelve weeks after just one dose. The results were striking. Nearly...
Pentagon Adds Psilocin to the Drug Testing Panel Starting October 1, 2025, the Department of Defense will begin military psilocin testing as part of its expanded Drug Demand Reduction Program. A recent memo confirms that service members’ samples will now be screened for psilocin, the metabolite of psilocybin mushrooms. Officials argue that psychedelic use poses risks...
Germany has taken a historic step by permitting psychiatrists to prescribe psilocybin for treatment‑resistant depression under a compassionate‑use framework. This marks the first time a European Union country has given doctors authority to administer the psychedelic compound outside of clinical trials. The Central Institute of Mental Health (CIMH) in Mannheim and Berlin’s OVID Clinic, both...
Fentanyl has become a leading driver of the overdose crisis in the United States, contributing to tens of thousands of deaths every year. Awareness and prevention have never been more urgent, which is why National Fentanyl Prevention and Awareness Day exists—to educate the public, promote harm reduction, and save lives.In preparation for this National Fentanyl...
A Cannabis Certificate of Analysis (COA) is a document provided by an accredited laboratory that details the testing results of a cannabis product. Understanding how to read a COA is crucial for consumers who want to ensure the safety and potency of their purchase. Here’s a guide to the key components typically found on a...
The 2018 Farm Bill, formally known as the Agriculture Improvement Act of 2018, marked a pivotal moment in the history of cannabis legislation in the United States. Among its broad-ranging provisions, the bill federally legalized hemp, a variety of the Cannabis sativa plant species, and its derivatives, thus distinguishing them from their psychoactive cousin, marijuana....
In the rapidly expanding cannabis market, THCa flower has emerged as both a hot trend and a legal gray area. Touted as “hemp” under the 2018 Farm Bill, THCa products offer effects nearly identical to traditional marijuana when smoked or vaped, while technically remaining legal in some states. But with popularity comes confusion—and potential risks. Whether...
What is Pink Cocaine / Tusi? Pink Cocaine, also known as “Tusi,” “Tucibi,” “Tusi Lavada,” “Venus,” and “Nexus,” is a dangerous drug mixture rapidly growing in popularity in the United States. First gaining prevalence in Latin America, this drug cocktail is often mistaken for its similar-sounding alternatives—but it is far from either cocaine or 2C-B, and...
