The drug supply is evolving again. Just when public health agencies and harm reductionists were starting to wrap their heads around xylazine and nitazene, a new veterinary sedative has entered the scene: medetomidine. It's stronger, less predictable, and even more dangerous. What Is Medetomidine, and Why Is It in the Fentanyl Supply? Medetomidine is a...
In our previous blog post, we explored the fascinating chemistry and effects of 1P‑LSD and its analogues. But one crucial element deserved its own deep dive: the rise of prodrugs in the research chemical (RC) world and how they reshaped the psychedelic landscape. If you’ve ever wondered how “legal LSD” became a thing...
Smart, safe, and genuinely useful gifts for psychonauts, festival lovers, and harm reduction enthusiasts. A Different Kind of Holiday Gift Guide Every December, gift guides for “stoners,” “ravers”, “festival goers,” and “psychedelic lovers” pop up across the internet—usually filled with mushroom mugs, novelty grinders, and psychedelic décor. Fun? Absolutely, but this year, gifting should go deeper. Alongside the fun...
Test kits and Narcan are two of the most powerful tools in harm reduction—but they serve completely different purposes. Understanding Harm Reduction: Proactive vs. Reactive Tools Testing is proactive harm reduction. It helps prevent overdoses by allowing you to identify what’s really in your substance before deciding to take it. Drug testing utilizes tools like fentanyl...
New research suggests that psychedelics may be capable of more than altering consciousness; they might also play a role in calming inflammation and balancing the immune system. Scientists studying compounds like LSD, psilocybin, and DMT are finding that these molecules interact with immune pathways in ways that could reshape how we treat...
A groundbreaking phase two clinical trial has found that a single 100-microgram (ug) dose of LSD, in its pharmaceutical formulation MM120, can significantly reduce symptoms of generalized anxiety disorder (GAD). What makes this finding especially noteworthy is that the relief lasted for up to twelve weeks after just one dose. The results were striking. Nearly...
We had an incredible time at Lost Lands 2025, where our team educated and served hundreds of attendees with test strips, reagent test kits, and harm reduction practices from Wednesday through Sunday. Set up in Camp Spinosaurus, we connected with festival-goers all weekend long, helping people feel confident in testing their substances, sharing harm...
DMT is known for producing short, powerful psychedelic experiences, but new research suggests its potential goes far beyond the trip. Scientists are now exploring how low, non-hallucinogenic doses of DMT could help heal the brain after a stroke. In this post, we’ll break down what the latest study found, what it means for the future...
If you remember when fentanyl first hit the scene, you know how fast the supply can turn into a minefield. Now, there’s another player in the mix: nitazenes. This family of synthetic opioids is so strong that some versions make fentanyl look weak. A new study out of the UK, published on August 9, 2025...
Pentagon Adds Psilocin to the Drug Testing Panel Starting October 1, 2025, the Department of Defense will begin military psilocin testing as part of its expanded Drug Demand Reduction Program. A recent memo confirms that service members’ samples will now be screened for psilocin, the metabolite of psilocybin mushrooms. Officials argue that psychedelic use poses risks...
